School of Behavioral and Brain Sciences

Karen M. Rodrigue

Assistant Professor

Research Interests

Understanding factors that contribute to individual differences in brain and cognitive aging over the lifespan, utilizing neuropsychology assessment, structural and functional MRI and PET imaging techniques

Curriculum Vitae


Email: [email protected]
Phone: 972-883-3738
Office: VP_8.20
Campus Mail Code: VP10
Website: Cognitive Neuroscience of Aging Lab


Dr. Karen Rodrigue is a leading researcher in the area of age-related changes in the brain in healthy aging and their impact on cognitive performance, as well as the study of the health modifiers of the neurocognitive aging process. Dr. Rodrigue recently examined the role of amyloid-beta deposition in non-pathological aging and investigated the effects of genetic risk and vascular risk factors on the accumulation of this Alzheimer’s disease biomarker. She is known for her cross-sectional and longitudinal studies of structural changes in the aging brain, the impact of hypertension on brain and cognitive health, and for studying the role of brain iron accumulation with aging. Dr. Rodrigue has been awarded a K99/R00 “Pathway to Independence” Award from the National Institute on Aging and, in 2007, her dissertation work on brain iron accumulation in aging was recognized with a Dissertation Research Award from the American Psychological Association. In 2013, Dr. Rodrigue was named a “Rising Star” by the American Psychological Society. She received her bachelor’s degree from Loyola University, her master’s degree from Emporia State University, and her PhD from Wayne State University in Detroit, Michigan.

Recent and Selected Representative Publications

Recent Articles in Peer-Refereed Journals

Ossenkoppele R, Jansen WJ, Rabinovici GD, Knol DL, van der Flier WM, et al., Rodrigue KM, Brooks DJ. (2015). Prevalence of amyloid PET positivity in dementia syndromes: a metaanalysis. JAMA. May 19;313(19):1939-1949.

Jansen WJ, Ossenkoppele R, Knol DL, Tijms BM, Scheltens P,et al., Rodrigue KM, et al., (2015). Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis. JAMA. May 19; 313(19):1924-1938.

Rieck, J. R., Rodrigue, K. M., Kennedy, K. M., Hebrank, A. C., Devous, M. D., Sr., Park, D.C. (2015). The effect of beta-amyloid on face processing in young and old adults: A multivariate analysis of the BOLD signal. Human Brain Mapping, 36, 2514-25-26.