Cellular mechanisms of memory consolidation, maintenance and extinction; memory disruption by aging, experience, or metabolic insult; memory restoration by nootropics
Dr. Tres Thompson is a leading researcher in the area of the neurobiology of aging and memory. His recent research focused on sex differences of short- versus long-term high-fat diets on spatial memory, hippocampal excitability, hormones, glucose regulation, and molecular signaling pathways. He also has examined the detailed mechanisms of memory consolidation linking the hippocampus and the amygdala. Dr. Thompson previously has studied stability versus plasticity of hippocampal place cells and the time course of mechanisms necessary for hippocampal-dependent memories. He is the founder of the neuroscience program in the School of Behavioral and Brain Sciences and has won numerous teaching awards at the school. He also has been an editorial board member for three neuroscience journals and serves on the Alzheimer’s Association Medical and Scientific Advisory Council. Dr. Thompson earned his bachelor’s and master’s degrees from California State University, San Bernardino, and his PhD from the University of Virginia, with postdoctoral training and faculty experience at Northwestern University Medical School.
Recent Articles in Peer-Refereed Journals
Underwood, E.L. and Thompson, L.T. (2016). High-fat diet impairs spatial memory and hippocampal intrinsic excitability, and sex-dependently alters circulating insulin and hippocampal insulinsensitivity. Biology of Sex Differences, 7, 9.
Underwood, E.L. and Thompson, L.T. (2016). A high-fat diet causes impairment in hippocampal memory and sex-dependent alterations in peripheral metabolism. Neural Plasticity, 501, 161985.
Lovitz, E.S. and Thompson, L.T. (2015). Memory-enhancing intra-basolateral amygdala clenbuterol infusion reduces post-burst afterhyperpolarizations in hippocampal CA1 pyramidal neurons following inhibitory avoidance learning. Neurobiology of Learning & Memory, 119, 34-41.View more