Laboratory of Jonathan E. Ploski, PhD
Assistant Professor
Behavioral and Brain Sciences,
Molecular and Cellular Biology
The University of Texas at Dallas
PhD in Biomedical Science from Mount Sinai School of Medicine |
6/2004 |
Mentor: Aurelian Radu, PhD |
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| Postdoctoral training | |
Yale Medical School, Department of Psychiatry |
6/2004-9/2006 |
Mentor: Ronald S. Duman PhD |
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| Yale University, Department of Psychology | 9/2006-5/2010 |
Mentor: Glenn E. Schafe, PhD |
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RESEARCH INTERESTS
My research interests are directed toward elucidating the molecular and cellular mechanisms of neuronal plasticity that govern emotional memory as well as identifying the causes and consequences of aberrant forms of plasticity that occur in psychiatric disorders, such as anxiety. Collectively my research utilizes a myriad of molecular, biochemical and behavioral approaches.
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Amygdala neurons within the rat brain are infected with Adeno-Associated Virus expressing Green Fluorescence Protein (GFP) and a Silencing RNA (siRNA) to suppress the expression of a specific neuronal gene. (a-b). Localization of GFP-expressing cells from two different rostro-caudal levels. Note the significant amount of infection in lateral nucleus of the amygdala (LA) and the basal nucleus of the amygdala (B). The central nucleus of the amygdala (CE) and surrounding cortical regions are not transfected. The cannula track is depicted by arrows. (c) Higher level (20X) magnification of transfected cells from panel B. (d). Brightfield image of the same section depicted in panel B, showing the location of the cannula track (arrows). |
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