Dr. Breen’s research interests concern the biogenesis of the mammalian mitochondrial oxidative phosphorylation system, the regulation of eukaryotic gene expression and the characterization of the role of mitochondria in neurodegenerative diseases, such as Alzheimer’s disease.
Dr. Bulla’s research interests are in the area of invertebrate and microbial molecular biology with particular focus on the biochemical and biophysical characterization of insecticidal toxin receptors in insects.
Dr. Burr’s research interests involve eukaryotic cell growth regulation and oncogensis. He is currently focusing his research on the oncogenic transformation of cells by Rous Sarcoma Virus (RSV).
Dr. Cirillo joined the UTD faculty after retiring from the State University of New York at Stony Brook as Professor Emeritus of Biochemistry. He received a B.A. in Biology from the University of Buffalo, an M.S. from New York University, and PhD in Zoology from UCLA. His major research interest on the mechanism of sugar transport ended with the publication of the complete DNA sequence of the yeast galactose transporter.
The goal of Dr. D’Mello’s laboratory is to understand how apoptosis (programmed cell death) is regulated in neurons of the mammalian brain.While apoptosis is a normal feature during early neurodevelopment, aberrant induction of apoptosis leading to undesirable neuronal loss occurs in several neurodegenerative diseases and following stroke or traumatic head injury.
Dr. DeJong’s research focuses on the factors and mechanisms responsible for the transcription of eukaryotic genes. Prior to joining the faculty at UTD, Dr. DeJong was a Postdoctoral Associate with Dr. Robert Roeder where he focused on RNA polymerase II transcription.
Dr. Draper’s research interests include the molecular pathogenesis of protein toxins, such as cholera toxin, membranes trafficking in eukaryotic cells, and the new field of bionanotechnology.
Dr. González focuses his research on the role of exopolysaccharides in the nodulation of legumes by rhizobia and the molecular genetics of plant-microbe interactions. Before joining the staff at UTD, Dr. González was a Postdoctoral Fellow at the Massachusetts Institute of Technology where he focused his research on molecular signals.
Dr. Goodman’s research program over the past twenty-five years has dealt with a macromolecular structure on the cytoplasmic surface of eukaryotic membranes, called the spectrin membrane skeleton. More recently he has turned his attention to Sickle Cell Disease. In a recent collaborated phase II human trial, it was demonstrated that N-acetyl cysteine, or NAC, can substantially reduce the rate of painful vasoocclusive episodes (sickle cell crisis).
Dr. Gray’s research interests include structures of polynucleotides studied by circular dichroism spectroscopy and the structures of DNA-protein complexes studied by CD spectra, NMR, and neutron diffraction techniques.
Dr. Hannig’s research interests include proteinprotein interactions, genetic and biochemical analysis of translation initiation factors, and protein synthesis and its regulation in eukaryotes.
Dr. Levene’s research interests involve protein-DNA interactions in site-specific recombination and the structure and dynamics of nucleic acids in solution.
Dr. Marsh’s research interests focus on subcellular structure. He is involved in projects concerning the identification and characterization of nuclear matrix proteins, cell surface lectins, and the protein crosslinking enzyme transglutaminase which has multiple functions in cell physiology.
Dr. Miller’s research interests include the structure and organization of mitochondrial DNA, mitochondrial gene expression, RNA editing, and mitochondrial biogenesis.
Dr. Moltz joined the faculty in 1995. His primary responsibility is to offer a human anatomy and physiology curriculum to the pre-professional healthcare student.
The goal of Dr. Pace’s research is to design novel treatments for sickle cell disease. Drug studies to understand the molecular mechanisms involved in fetal hemoglobin synthesis, to block the negative effects of the sickle gene is the main strategy used in the Pace laboratory.
Dr. Reitzer’s research involves the regulation of gene expression and metabolism in Escherichia coli and pathogenic bacteria.
Dr. Rippel joined the faculty in 1999 as a Senior Lecturer. His primary instructional duties include teaching a Biotechnology Laboratory BIO2V00) for non-majors,and the junior-level Biochemistry Laboratory (BIO4380).
Dr. Sapozhnikov received his Diploma of a Medical Doctor as well as the PhD degree in Russia. He was the Head of the Research Group for the primary prevention and non-drug treatment of cardiovascular diseases at the USSR Research Cardiology Center for the Academy of the Medical Sciences in Moscow, Russia.
Stephen Spiro is interested in the regulation of bacterial gene expression by environmental signals, and the consequences of gene regulation for the physiological adaptation to stress.
Dr. Xia's research involves femtochemistry in an effort to unlock the mysteries of conformational dynamics.
Dr. Zhang’s research focuses on oxygen sensing, heme signaling and molecular actions of environmental neurotoxicants.
- Updated: January 9, 2008
