Electrochemical Light‐Emitting Devices and Biosensors
Nov 23
(4 - 5 p.m.)
(4 - 5 p.m.)
Location:
TI Auditorium ECSS 2.102
TI Auditorium ECSS 2.102
Presented by the Department of Physics and the Sigma XI Research Society
Refreshments will be served at 3:30 PM
Dr. Jason Slinker
California Institute of Technology
The interplay between ionic and electronic charges in soft materials can be controlled to yield unique electrical properties an novel device capabilities. My research with these electrochemical materials spans two device areas: light‐emitting devices and biosensors.
Organic electroluminescent devices are currently under development for display and lighting applications due to their potentialas low cost, high efficiency devices. However, a significant barrier to their implementation arises in the complexity of the methods currently used to create high efficiencyorganic devices. Alternatively, organic electroluminescent devices from ionic transition metal complexes (iTMCs) offer simplicity of fabrication and potential for high performance. Our work with iTMC devices has involved understanding the underlying physics, improving efficiency, extending the range of available colors, ascertaining modes of degradation, and inventing practical architectures for display and lighting applications. Concerning device physics, we utilized electric force microscopy to distinguish between models of operation. We demonstrated the first instances of efficient yellow and green iTMC devices with power efficiencies comparable to incandescnt bulbs. To understand factors governing lifetime, we used mass spectroscopy and Raman spectrometry to identify degradation products formed during device operation. We produced monolithic, scalable lighting panels from iTMC devices with intrinsic fault tolerance and direct outlet operation at 120 volts and 60 hert. We also formed electrospun light‐emitting nanofibers with nanoscale emission zones for high‐resolution display and spectroscopy applications.
Detection of biomarkers such as DNA and proteins is of utility for laboratory assays as well as clinical and point‐of‐care disease diagnostics. Towards these ends, electrical and electrochemical devices are under development for biosensing applications, offering low cost, ease of portability, and multiplexed capability. However, despite the recent proliferation of electrical biosensors, relatively few examples of multiplexed sensors have been reported. We have created silicon chips with 16 DNA‐modified electrodes (DME chips) for multiplexed analysis of DNA and protein targets. DNA‐mediated electrochemistry was utilized as well‐ordered DNA facilitates charge transport through the base pair π‐stack, but distortion of the π‐stack, such as by mismatched bases or bending of the DNA by a protein, greatly attenuates the efficacy of charge transport. Multiplexed capability was demonstrated by distinguishing four DNA targets on a single DME chip, including one incorporating a single‐base mismatch. Multiplexed analysis also enabled site‐specific detection of a protein target, the restriction enzyme Alu1. These results suggest that DME chips facilitate sensitive, selective and label‐free detection of DNA and protein targets, beneficial for laboratory assays and clinical diagnostic applications.
See website for more information
Please Note: The UT Dallas campus is undergoing a significant amount of construction. Guests are advised to visit our campus map for updated route, construction, and parking information.
Tagged as Lectures/Seminars
Refreshments will be served at 3:30 PM
Dr. Jason Slinker
California Institute of Technology
The interplay between ionic and electronic charges in soft materials can be controlled to yield unique electrical properties an novel device capabilities. My research with these electrochemical materials spans two device areas: light‐emitting devices and biosensors.
Organic electroluminescent devices are currently under development for display and lighting applications due to their potentialas low cost, high efficiency devices. However, a significant barrier to their implementation arises in the complexity of the methods currently used to create high efficiencyorganic devices. Alternatively, organic electroluminescent devices from ionic transition metal complexes (iTMCs) offer simplicity of fabrication and potential for high performance. Our work with iTMC devices has involved understanding the underlying physics, improving efficiency, extending the range of available colors, ascertaining modes of degradation, and inventing practical architectures for display and lighting applications. Concerning device physics, we utilized electric force microscopy to distinguish between models of operation. We demonstrated the first instances of efficient yellow and green iTMC devices with power efficiencies comparable to incandescnt bulbs. To understand factors governing lifetime, we used mass spectroscopy and Raman spectrometry to identify degradation products formed during device operation. We produced monolithic, scalable lighting panels from iTMC devices with intrinsic fault tolerance and direct outlet operation at 120 volts and 60 hert. We also formed electrospun light‐emitting nanofibers with nanoscale emission zones for high‐resolution display and spectroscopy applications.
Detection of biomarkers such as DNA and proteins is of utility for laboratory assays as well as clinical and point‐of‐care disease diagnostics. Towards these ends, electrical and electrochemical devices are under development for biosensing applications, offering low cost, ease of portability, and multiplexed capability. However, despite the recent proliferation of electrical biosensors, relatively few examples of multiplexed sensors have been reported. We have created silicon chips with 16 DNA‐modified electrodes (DME chips) for multiplexed analysis of DNA and protein targets. DNA‐mediated electrochemistry was utilized as well‐ordered DNA facilitates charge transport through the base pair π‐stack, but distortion of the π‐stack, such as by mismatched bases or bending of the DNA by a protein, greatly attenuates the efficacy of charge transport. Multiplexed capability was demonstrated by distinguishing four DNA targets on a single DME chip, including one incorporating a single‐base mismatch. Multiplexed analysis also enabled site‐specific detection of a protein target, the restriction enzyme Alu1. These results suggest that DME chips facilitate sensitive, selective and label‐free detection of DNA and protein targets, beneficial for laboratory assays and clinical diagnostic applications.
See website for more information
Please Note: The UT Dallas campus is undergoing a significant amount of construction. Guests are advised to visit our campus map for updated route, construction, and parking information.
Tagged as Lectures/Seminars
