Comet Calendar, The Official Event Calendar for UT Dallas en-us This week's events for Communications at UT Dallas Center for Engineering Innovation Seminar with Dr. Eberhard O. Voit Friday, Feb 27
(2 p.m. - 3 p.m.)

Center for Engineering Innovation Special Seminar with Dr. Eberhard O. Voit (Georgia Tech and Emory University Medical School) - Friday, February, 27, 2015 at 2:00 p.m. in ECSS 3.503.

Topic: Computational Analysis of the Dopamine System: From Simple Models to System Simulation and the Discovery of Design Principles 

Two grand challenges have been declared as premier goals of computational systems biology. The first is the discovery of network motifs and design principles that help us understand and rationalize why biological systems are organized in the manner we encounter them rather than in a different fashion. The second goal is the development of computational models supporting the investigation of complex systems, in particular, as simulation platforms in personalized medicine and predictive health. Interestingly, most published systems models in biology contain maybe a handful to two dozen variables. They are usually too complicated for systemic analyses of organizing principles, but they are at the same time too coarse to allow detailed, reliable simulations of natural systems. While it may thus appear that the modeling efforts of the past have missed the declared targets of systems biology, I will argue in this presentation that midsized mesoscopic models are excellent starting points for pursuing both goals in computational systems biology.