Jung-Mo Ahn , Ph.D.
Organic and MedicinalChemistry
Research Group
Education
B.S., Seoul National University (1992)
M.S., Seoul National University (1994)
Ph.D., University of Arizona (2000)
Postdoctoral Associate, The Scripps Research Institute (2001–04)
Research Description
The central theme of my research is to understand the chemistry and biology of peptides and proteins and to develop new approaches for manipulating these properties with purposefully designed small organic molecules. We employ chemical synthesis and combinatorial chemistry as well as spectroscopic and biophysical methods to accomplish these aims. Projects include:
- Development of peptidomimetics for the treatment of Diabetes Mellitus
- Development of therapeutic agents for biodefense against bacterial infection
Selected Publications
Ahn, J.-M.; Wentworth, P. Jr.; Janda, K.D. “Probing lipase/esterase libraries for lipid A hydrolases – discovery of biocatalysts for the detoxification of bacterially-expressed recombinant protein.” Chem. Commun. (2004) 364-365.
Ahn, J.-M.; Wentworth, P. Jr.; Janda, K.D. “Soluble Polymer-Supported Convergent Parallel Library Synthesis.” Chem. Commun. (2003) 480-481.
Ahn, J.-M.; Gitu, P.M.; Medeiros, M.; Swift, J.R.; Trivedi, D.; Hruby, V.J. “A New Approach to Search for the Bioactive Conformation of Glucagon: Positional Cyclization Scanning.” J. Med. Chem. (2001) 44: 3109-3116.
- Updated: November 28, 2006