This image illustrates a new class of MRI "activatable" agents called PARACEST agents that can be turned on-and-off by switching on a RF pulse.
Chemistry Projects
“Catalytic effects of apoferritin interior surface residues on water exchange in lanthanide complexes”, O Vasalatiy, P Zhao, S Zhang, S Aime & AD Sherry, Contrast Media & Mol Imaging, 1, 1-5 (2006).
“Europium(III) Macrocyclic Complexes with Alcohol Pendant Groups as Chemical Exchange Saturation Transfer (CEST) Agents” M Woods, DE Woessner, P Zhao, A Pasha, M-Y Yang, C-H Huang, O Vasalitiy, JR Morrow, AD Sherry” J. Amer. Chem. Soc. 128, 10155-10162 (2006).
“High Resolution pHe Imaging of Rat Glioma using pH-dependent relaxivity”, ML Garcia-Martin, GV Martinez, N Raghunand, AD Sherry, S Zhang & RJ Gillies, Magn. Reson. Med., 55, 309-315 (2006).
“Paramagnetic Lanthanide Complexes as PARACEST Agents for Medical Imaging”, M Woods, DE Woessner & AD Sherry, Chem Soc Rev, 35, 500-511 (2006).
“Equilibrium and Formation/Dissociation Kinetics of some Lanthanide(III)-PCTA complexes”, G Tircsó, Z Kovács, & A D Sherry, Inorg. Chem., 45, 9269-9280 (2006).
“Sensitivity Enhancement of Multidimensional NMR experiments by Paramagnetic Relaxation Effect”, S Cai, C Seu, Z Kovacs, AD Sherry & Y Chen, J. Am. Chem. Soc., 128, 13474-13478 (2006).
“Multifunctional Polymeric Micelles as Cancer-Targeted, MRI-Ultrasensitive Drug Delivery Systems”, N Nasongkla, E Bey, J Ren, H Ai, C Khemtong, JG Setti, SF Chin, AD Sherry, DA Boothman, J Gao, Nano Letters, 6, 2427-2430 (2006).
“PARACEST agents for Molecular Imaging” in Molecular & Cellular MR Imaging, Edited by J Bulte & M Modo, AD Sherry & M Woods, CRC Press, Chapter 6, pp. 101-122 (2007).
“A Bridge to Coordination Isomer Selection in Lanthanide(III) DOTA-tetraamide Complexes”, J Vipond, M Woods, P Zhao, G Tircso, Jimmy Ren, GE Kiefer, Zoltan Kovacs & AD Sherry, Inorg. Chem., 46, 2584-2595 (2007).
“Spectral properties of a bifunctional PARACEST europium chelate: an intermediate for targeted imaging applications”, C Adair, M Woods, P Zhao, A Pasha, PM Winter, GM Lanza, P Athey, AD Sherry, GE Kiefer, Contrast Media & Molecular Imaging 2, 55-58 (2007).
“Potentiometric and Relaxometric Properties of Gadolinium-based MRI Contrast Agent for Sensing Tissue pH”, FK Kálmán, M Woods, P Jurek, M Spiller, P Caravan, G Tircsó, R Király, E Brücher & AD Sherry, Inorg. Chem., 46, 5260-5270 (2007).
“MRI detection of Paramagnetic Chemical Exchange Effects in mice kidneys in vivo”, E. Vinogradov, H He, A Lubag, JA Balschi, AD Sherry & RE Lenkinski, Magn Reson Med., 58, 650-655 (2007).
“Synthesis and characterization of DOTA-(amide)4 derivatives: equilibrium and kinetic behavior of their lanthanide(III) complexes”, A Pasha, G Tircso, ET Benyo, E Brucher & AD Sherry, Eur. J. Inorg. Chem., 4340-4349 (2007).
“Albumin-binding PARACEST Agents”, MM Ali, M Woods, E Suh, G Tircsó, V Kodibagkar & AD Sherry, J. Biol. Inorg. Chem., 12, 855-865 (2007).
“Modulation of Water Exchange in Europium(III) DOTA-tetraamide Complexes via Electronic Substituent Effects”, SJ Ratnakar, Mark Woods, AJM Lubag, Z Kovács & AD Sherry, J. Amer. Chem. Soc., 130, 6-7 (2008).
Updated: February 13, 2008
