About the AIRC Faculty Contacting the AIRC Mouse Imaging Core Facility Research Areas Opportunities
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About the AIRC

Academic Title Assistant Professor
Primary
Appointment
Radiology
Secondary Appointment Advanced Imaging Research Center
School Graduate School of Biomedical Sciences
Degree Program Radiological Sciences
Biomedical Engineering

Xiankai Sun, PhD

Research Overview
The research interest of my laboratory is primarily in developing novel molecular imaging probes for the early detection of biological abnormalities and the efficacy evaluation of disease treatments. The general approach involves multidisciplinary collaborations to identify functional molecules or substrates for specific disease targets; modify the molecules; and design precursors so that, while maintaining the desired biological activity, the compounds can be tagged with radioisotopes that emit positrons or gamma rays for non-invasive detection and investigation of diseases using Positron Emission Tomography (PET) or Single Photon Emission Computed Tomography.

Current research projects in my laboratory include:

  1. Preparation of biocompatible nanosized scaffolds to present multiple functionalities for detection and intervention of disease states
  2. Design of multivalent or multiplexed agents for multi-modality imaging of cancer and metastases
  3. Development of MRI, PET, and MRI/PET imaging probes for non-invasive longitudinal monitoring of the pancreatic beta cells.

Contact email: xiankai.sun@utsouthwestern.edu

Research Interests

Develop PET/SPECT/MRI imaging probes to assess biological abnormalities