Principal Investigator


Dr. Jie Zheng


Research Assistant Professor


Dr. Mengxiao Yu


Postdoctoral Fellows


Dr. Shaoheng Tang


PhD Candidates


Ms. Bujie Du


Mr. Xingya Jiang


Mr. Xuhui Ning


Mr. Chuanqi Peng


Ms. Jing Xu


Graduate Students


Mr. Yingyu Huang


Undergraduate Students


Ms. Phoebe Carter


Mr. Anthony Dao


Mr. Greg Zhang 


Former Group Members


Dr. Jinbin Liu (Postdoc)

Dr. Shengyang Yang (Postdoc)

Dr. Jing Yu (Postdoc)

Dr. Zhanghua Zeng (Postdoc)

Dr. Liang Zhao (Postdoc)


Ms. Jennifer Chilek (Graduate)

Dr. Chen Zhou (Graduate)

Dr. Shasha Sun (Graduate)

Dr. Rodrigo Vinluan III  (Graduate)

Ms. Jessica Jacobe (Graduate)





Ms. Sheby Alexander (Undergraduate)

Mr. Chris Alameddin (Undergraduate)

Mr. Michael Anyirah (Undergraduate)

Mr. Sishan Chen (Undergraduate) 

Mr. Giovanni Contello (Undergraduate) 

Mr. Andrew Dean (Undergraduate) 

Ms. Melissa Gannaway (Undergraduate)

Ms. Julia Hankins (Undergraduate)

Ms. Grace Kong (Undergraduate)

Mr. Stephen McMahon (Undergraduate)

Mr. Husain Mogri (Undergraduate)

Mr. Ali Mozayan (Undergraduate)

Mr. Justin Sullins (Undergraduate)

Mr. Joel Taylor (Undergraduate)

Mr. Jonathan Wang (Undergraduate)



Ms. Chelsea Carson (High School)

Ms. Karen Chen (High School)

Ms. Clare Jensen (High School)

Ms. Rebecca John (High School)

Ms. Amy Xia (High School)

Mr. Robert Yao (High School)


Mengxiao Yu


Research Assistant Professor



Office: NSERL 2.440


E-mail: [email protected]


Mailing Address:


BE26, The University of Texas at Dallas, 800 W Campbell Rd. Richardson, TX 75080


Education Background


Ph.D. Laboratory of Advanced Materials, Fudan University, Shanghai, China, 2009.


B.S.  Department of Chemistry, Beijing Normal University, Beijing, China, 2004.

Research Area


Intracellular Labeling and Drug Delivery.


Honors and Awards


Best Poster in Biomaterials and Tissue, UT Metroplex Day, 2010.


Selected Publications


1. J.B. Liu, P.N. Duchesne, M.X. Yu, X.Y. Jiang, X.H. Ning, P. Zhang, J. Zheng. “Luminescent Gold Nanoparticles with Size-independent Emissions”, Angew. Chem. Int. Ed., 2016, accepted. 


2. M. X. Yu, J. C. Zhou, B. J. Du, X. H. Ning, C. Authement, L. Gandee, P. Kapur, J. T. Hsieh, J. Zheng. “Noninvasive Staging of Kidney Dysfunction Enabled by Renal Clearable Luminescent Gold Nanoparticles”, Angew. Chem. Int. Ed., 55, 2787-2791 (2016) (Highlighted as VIP).


3.M. X. Yu, J. B. Liu, X. H. Ning, J. Zheng*. “High-contrast Noninvasive Imaging of Kidney Clearance Kinetics Enabled by Renal Clearable Nanofluorophores”. Angew. Chem. Int. Ed. 54, 15434-15438 (2015).


4. M. X. Yu, J. Zheng*. “Clearance Pathways and Tumor Targeting of Imaging Nanoparticles”. ACS Nano, 2015, 9, 6655–6674 (2015) (Invited review article, Highlighted as one of the "top 5 most read articles" of ACS Nano in July 2015).


5. R. D. Vinluan III, M. X. Yu, M. Gannaway, J. Sullins, J. Xu, Jie Zheng*. “Labeling Monomeric Insulin with Renal-Clearable Luminescent Gold Nanoparticles”. Bioconjugate Chem., DOI: 10.1021/acs.bioconjchem.5b00490 (2015).


6. R. Vinluan III, J. Liu, C. Zhou, M. Yu, S. Yang, A. Kumar, S. Sun, A. Dean, X. Sun, J. Zheng*. "Glutathione-Coated Luminescent Gold Nanoparticles: A Surface Ligand for Minimizing Serum Protein Adsorption", ACS Appl. Mater. Interfaces, 2014, DOI:10.1021/am5031374.


7. S. Sun, C. Zhou, S. Chen, J.B. Liu, J. Yu, J. Chilek, L. Zhao, M.X. Yu, R. Vinluan, B. Huang, and J. Zheng, "Surface-Chemistry Effect on Cellular Response of Luminescent Plasmonic Silver Nanoparticles", Bioconjugate Chemistry, 2014, DOI: 10.1021/bc500008a.


8. J. B. Liu, M. X. Yu, C. Zhou, J. Zheng*. "Renal Clearable Inorganic Nanoparticles: A New Frontier of Bionanotechnology". Mater. Today 16, 477-486 (2013).


9. J.B. Liu, M.X. Yu, X. Ning, C. Zhou, S.Y. Yang, and J. Zheng*, "PEGylation and Zwitterionization: Pros and Cons in Renal Clearance and Tumor Targeting of Near-IR-Emitting Gold Nanoparticles", Angew. Chem. Int. Ed. 52, 12572-12576 (2013) (Highlighted as VIP)


10. C. Zhou, S. Yang, J. Liu, M.X. Yu, and J. Zheng, “Luminescent Gold Nanoparticles: A New Class of Nanoprobes for Biomedical Imaging”, Exp. Bio. Med., 2013, accepted.


11. J. Liu, M. Yu, C. Zhou, S. Yang, X. Ning, and J. Zheng, “Passive Tumor Targeting of Renal Clearable Luminescent Gold Nanoparticles: Long Tumor Retention and Fast Normal Tissue Clearance”, J. Am. Chem. Soc., 2013, 135, 4978-4981 (2013).


12. J. Zheng*, C. Zhou, M. X. Yu, J. B. Liu. "Different sized luminescent gold nanoparticles". Nanoscale 4, 4073-4083 (2012) (Highlighted as one of the "top 10 most accessed articles" of Nanoscale in June and July 2012).


13. C. Zhou, G. Y. Hao, P. Thomas, J. B. Liu, M. X. Yu, S. S. Sun, O.K. Oez, X. K. Sun, J. Zheng*. "Near-Infrared Emitting Radioactive Gold Nanoparticles with Molecular Pharmacokinetics". Angew. Chem. Int. Ed. 51, 10118-10122 (2012).


14. S. Y. Yang, C. Zhou, J. B. Liu, M. X. Yu, J. Zheng*. "One-Step Interfacial Synthesis and Assembly of Ultrathin Luminescent AuNPs/Silica Membranes". Adv. Mater. 24, 3218-3222 (2012).


15. M. Yu, C. Zhou, J. Liu, J. D. Hankins, J. Zheng, “Luminescent Gold Nanoparticles with pH De-pendent Membrane Adsorption”, J. Am. Chem. Soc., 133, 11014-11017 (2011).


16. J. Liu, C. Zhou, M. Yu, J. Zheng, "Decomposition of Amino Acids Catalyzed by Plasmonic Gold Nanoparticles", Sci. Adv. Mater., 4, 813-818 (2012).


17. C. Y. Li, M. X. Yu, Y. Sun, Y. Q. Wu, C. H. Huang, F. Y. Li*. "A Nonemissive Iridium(III) Complex That Specifically Lights-Up the Nuclei of Living Cells". J. Am. Chem. Soc. 133, 11231-11239 (2011) (Highlighted by Chemical and Engineering News).


18. C. Zhou, C. Sun, M. X. Yu, Y. P. Qin, J. G. Wang, M. Kim, J. Zheng*. "Luminescent Gold Nanoparticles with Mixed Valence States Generated from Dissociation of Polymeric Au(I) Thiolates". J. Phys. Chem. C 114, 7727-7732 (2010).


19. M.X. Yu, F.Y. Li, Z.G. Chen, H. Hu, C. Zhan, H. Yang, C.H. Huang, “Laser Scanning Up-conversion Luminescence Microscopy for Imaging Cells Labeled with Rare-earth Nanophospors”, Anal. Chem., 81, 930–935 (2009).


20. L.Q. Xiong, M.X. Yu, M.J. Cheng, X.Y. Zhang, C.J. Xu, F.Y. Li, “A Photostable Fluorescent Probe for Targeted Imaging of Tumour Cells Possessing Integrin αvβ3”, Mol. Biosyst., 5, 241243 (2009).


21. M.X. Yu, M. Shi, Z.G. Chen, F.Y. Li, X.X. Li, Y.H. Gao, J. Xu, H. Yang, Z.G. Zhou, T. Yi, C.H. Huang, “Highly Sensitive and Fast Responsive Fluorescence Turn-on Chemodosimeter for Cu2+ and its Application in Live Cell Imaging”, Chem. Eur. J., 14, 68926900 (2008).


22. M.X. Yu, Q. Zhao, L.X. Shi, F.Y. Li, Z.G. Zhou, H. Yang, T. Yi, C.H. Huang, Cationic Iridium(III) Complexes for Phosphorescence Staining in the Cytoplasm of Living Cells”, Chem. Comm., 2115–2117 (2008).


23. M. Zhang, M.X. Yu, F.Y. Li, M.W. Zhu, M.Y. Li, Y.H. Gao, L. Li, Z.Q. Liu, J.P. Zhang, D.Q. Zhang, T. Yi, C.H. Huang, A Highly Selective Fluorescence Turn-on Sensor for Cysteine/Homocysteine and its Application in Bioimaging”, J. Am. Chem. Soc., 129, 10322–10323 (2007).

[Contact us]

2.440 NSERL Building, The University of Texas at Dallas
Tel: 972-883-5768 (Dr. Zheng), 972-883-5769 (Lab)