All UTD students and faculty are welcome to attend (and have some pizza).

Topics in Neuroscience Syllabus

HCS 8V50.021

Summer, 2007

Instructors: Dr. Michael P. Kilgard

Offices: JO 4.304

Office Hours: by appointment

Office Phone: x2339

E-mail: kilgard@utdallas.edu

Class Times: 12-1:30 pm TBA Location: GR4.301 (Green Fishbowl)

12-1pm Friday Location: MP2.204 (the Neuroscience Conference Room)

Course Objectives:

The overall objective of the course is to increase understanding of recent developments in neuroscience through discussion and analysis of primary articles published in high impact journals. Each week we will cover two journal articles in depth. No text book is required for the class. Readings will be from seminal or provocative articles chosen by the participants.

Student Assessment:

Students registered for credit will be expected to attend all class meetings, participate in all discussions, and present at least two articles over the course of the semester. Other class participants will be requested to present one article during the semester. Presentations should be thorough and clear enough so that a participant need not have read the article before the class meeting in order to participate in the discussion. The use of computer-based presentations, rather than overheads, are encouraged. A computer and video projector will be available at each class. The course is pass/fail. No letter grades will be issued.

Readings:

Readings for the class will be selected by the participants. The readings for each week will be announced during the previous class, at the latest. The articles must be available on-line. Presenters are asked to email a link to all participants providing a site where the article can be downloaded. The readings should be selected from one of the following journals (Nature, Science, Nature Neuroscience, Journal of Neuroscience, Journal of Neurophysiology, Neuron, PNAS). If a participant wishes to present an article from a different journal, please ask one of the instructors for permission.

Summer 2007 Topics in Neuroscience Schedule:

Date	Presenter	Paper
5-14	Kilgard	Organizational Meeting
5-21	Vikram	Perinatal exposure to a noncoplanar polychlorinated biphenyl alters tonotopy, receptive fields, and plasticity in rat primary auditory cortex
	Kilgard	Potentiation of cortical inhibition by visual deprivation
6-4	Justin	Top-Down Versus Bottom-Up Control of Attention in the Prefrontal and Posterior Parietal Cortices
	Atzori	Coordinated memory replay in the visual cortex and hippocampus during sleep
6-11	Raj	Developmental hearing loss eliminates long-term potentiation in the auditory cortex
	Ben	Between-subject transfer of emotional information evokes specific pattern of amygdala activation
6-18	Jai	Transformation of temporal properties between auditory midbrain and cortex in the awake Mongolian gerbil
	Jayme	Neuronal competition and selection during memory formation
6-25	Ankur	Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice
	Vikram	Greater disruption due to failure of inhibitory control on an ambiguous distractor
7-2	Lu	Multiple views of the response of an ensemble of spectro-temporal features support concurrent classification of utterance, prosody, sex and speaker identity
	McIntyre	Learning induces long-term potentiation in the hippocampus
7-9	Ben	Environmental noise retards auditory cortical development.
	Justin	Neural Mechanisms of Visual Attention: How Top-Down Feedback Highlights Relevant Locations
7-16	Jai	When the Brain Loses Its Self: Prefrontal Inactivation during Sensorimotor Processing
	Raj	Functional Characterization of Intrinsic Cholinergic Interneurons in the Cortex
7-23	Ankur	Postsynaptic Receptor Trafficking Underlying a Form of Associative Learning
	Amanda	Homeostatic Regulation of Eye-Specific Responses in Visual Cortex During Ocular Dominance Plasticity
7-30	Atzori	The neuronal representation of pitch in primate auditory cortex.
	Vikram	Multimodal fast optical interrogation of neural circuitry
8-6	Kilgard	Efficient auditory coding
	Vikram	Prefrontal regions orchestrate suppression of emotional memories via a two-phase process
8-13	Raj	Co-activation of the secondary somatosensory and auditory cortices facilitates frequency discrimination of vibrotactile stimuli.

Spring 2006 Sensory Neuroscience Schedule:

Date	Presenter	Paper
1-19	Shveta	Collins CE, Xu X, Khaytin I, Kaskan PM, Casagrande VA, Kaas JH. Optical imaging of visually evoked responses in the middle temporal area after deactivation of primary visual cortex in adult primates. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5594-9.
	Amanda	Decreased Input-Specific Plasticity of the Auditory Cortex in Mice Lacking M1 Muscarinic Acetylcholine Receptors. Zhang Y, Hamilton SE, Nathanson NM, Yan J. Cereb Cortex. Nov 16, 2005
1-26	Rafael
	Jeff	Spaceflight Induces Changes in the Synaptic Circuitry of the Postnatal Developing Neocortex J. DeFelipe, J.I. Arellano, A. Merchán-Pérez, M.C. González-Albo, K. Walton3 and R. Llinás Cerebral Cortex, Vol. 12, No. 8, 883-891, August 2002
2-2	Rafael
	Justin
2-9	Amee	The spatial localization deficit in visually deprived kittens. Gingras G, Mitchell DE, Hess RF. Vision Res. 2005 Apr;45(8):975-89.
	Cauller	Peripheral neural implants
2-16	Kilgard	Receptive-field modification in rat visual cortex induced by paired visual stimulation and single-cell spiking. Meliza CD, Dan Y. Neuron. 2006 Jan 19;49(2):183-9.
2-23	Amanda	Prior experience enhances plasticity in adult visual cortex. Nat Neurosci. 2006 Jan;9(1):127-32 Hofer SB, Mrsic-Flogel TD, Bonhoeffer T, Hubener M.
	Lomber
3-2	Amee	Neuroplasticity after unilateral visual cortex damage in the newborn cat. Behav Brain Res. 2004 Aug 31;153(2):557-65. Rushmore RJ, Payne BR.
	Jeff	Activity in prefrontal cortex during dynamic selection of action sequences Bruno B Averbeck, Jeong-Woo Sohn & Daeyeol Lee Nat Neurosci. 2006 Feb; 9(2):276-82
3-16	Raj ?
	Vikram	Multisensory plasticity in congenitally deaf mice: How are cortical areas functionally specified? Neuroscience. 2006 Mar 7 Hunt DL, Yamoah EN, Krubitzer L.
3-23	Humberto	Dopamine modulates use-dependent plasticity of inhibitory synapses. J Neurosci. 2004 Jun 2;24(22):5162-71. Baimoukhametova DV, Hewitt SA, Sank CA, Bains JS.
3-30	Vikram	Transcranial fluorescence imaging of auditory cortical plasticity regulated by acoustic environments in mice. Takahashi K, Hishida R, Kubota Y, Kudoh M, Takahashi S, Shibuki K. Eur J Neurosci. 2006 Mar;23(5):1365-1376
4-6	Dinh	An Investigation into the Role of Cortical Synaptic Depression in Auditory Processing S L Denham and M J Denham
	Ashok	Residual function in peripheral nerve stumps of amputees: implications for neural control of artificial limbs. Dhillon GS, Lawrence SM, Hutchinson DT, Horch KW. J Hand Surg [Am]. 2004 Jul;29(4):605-15
4-13	Justin	Remodeling of synaptic structure in sensory cortical areas in vivo. J Neurosci. 2006 Mar 15;26(11):3021-9. Majewska AK, Newt on JR, Sur M.
	Vikram	Development of spectral and temporal response selectivity in the auditory cortex.Proc Natl Acad Sci U S A. 2005, 102(45):16460-5. Chang EF, Bao S, Imaizumi K, Schreiner CE, Merzenich MM.
4-20	Atzori	Reverse replay of behavioural sequences in hippocampal place cells during the awake state. David J. Foster & Matthew A. Wilson Nature Vol 440, 30 March 2006
	Raluca	Protein phosphatase 1 is a molecular constraint on learning and memory. Genoux D, Haditsch U, Knobloch M, Michalon A, Storm D, Mansuy IM Nature. 2002 Aug 29;418(6901):970-5
4-27	Jeff	Posterior Auditory Field Networks Underlying Sound Localization in Cat

Fall 2005 Auditory Neuroscience Schedule:

Date	Presenter	Paper
8/18	Dr. Kilgard	Postsynaptic Receptor Trafficking Underlying a Form of Associative Learning, Rumpel S, LeDoux J, Zador A, Malinow R. Science. 308:83-8, 2005.
8/25	Vikram	Active listening: Task-dependent plasticity of spectrotemporal receptive fields in primary auditory cortex. Fritz J, Elhilali M, Shamma S. Hearing Research 2005 Aug;206(1-2):159-76.
	Rafael