Publications

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Peer-reviewed Papers (click on links to read papers)

Abstracts (reverse chronological order)

1. Greer, T.L., Trivedi, M.H. & Thompson, L.T. (2005). Impaired delay and trace eyeblink conditioning performance in major depressive disorder. Journal of Affective Disorders, 86, 235-245.

2. Moller, A.R. & Thompson, L.T. (2003). Central neuronal plasticity in tinnitus: Functional assessments in the inferior colliculus and the hippocampus. Tinnitus Today, 28, 20.

3. Thompson, L.T., Lea, P., Seif, T. & Bui, W. Aging strain-selective deficits in rat spatial learning depend on the definition of 'impaired'. Neurobiology of Aging, in preparation.

4. Thompson, L.T. & Gant, J.C. Spatial learning and regulation of post-synaptic excitability: A preserved mechanism expressed in young and aging CA1 pyramidal neurons. Journal of Neuroscience, in preparation.

5. Gant, J.C. & Thompson, L.T. Calmodulin inhibitors enhance post-synaptic excitability in young and aging CA1 neurons. Journal of Neurophysiology, in preparation.

6. Thompson, L.T. & Lea, P. D-cycloserine facilitates complex spatial learning in rats: Age- and dose-dependence of effects. Behavioral Neuroscience, in preparation.

7. Greer, T.L. & Thompson, L.T. Associative eyeblink conditioning and aging: Cross-sectional analyses of deficits in discrimination and reveral learning. Behavioral Neuroscience, in revision.

8. Thompson, L.T., Gant, J.C., Velasco, R., & Vachha, B. Aging reverses complementary expression of CaM-KII and calcineurin immunoreactivity in rat hippocampus. Hippocampus, in preparation.

9. Thompson, L.T., Goble, T.J. & Farmer, G.E. D-cycloserine enhances place-cell location-specificity in a novel manner. Learning and Memory, in preparation.

10. Goble, T.J., Moller, A. & Thompson, L.T. Place-field plasticity in an experimental model of tinnitus: Evidence for persistent non-classical sensory pathway plasticity. Nature Neuroscience, in preparation.

11. Disterhoft, J.F., Carrillo, M.C., Thompson, L.T., McNaughton, B., & Gabrielli, J. Nimodipine reverses impairments in eyeblink conditioning in the most impaired but clinically 'normal' aging humans. Psychobiology, in preparation.

12. Oh, M.M., Power, J.M., Thompson, L.T., & Disterhoft, J.F. (2000). Apamin increases the excitability of rabbit CA1 hippocampal pyramidal neurons. Neuroscience Research Communications, 27, 135-142.

13. Moyer, J.R., Power, J.M., Thompson, L.T. & Disterhoft, J.F. (2000). Increased excitability of aged rabbit CA1 neurons after trace eyeblink conditioning. Journal of Neuroscience, 20, 5476-5482.

14. Oh, M.M., Power, J.M., Thompson, L.T., & Disterhoft, J.F. (1999). Metrifonate reduces post-burst afterhyperpolarizations in aging CA1 neurons. Journal of Neuroscience, 19, 1814-1823.

15. Thompson, L.T. & Disterhoft, J.F. (1997). Age- and dose-dependent facilitation of associative eyeblink conditioning by D-cycloserine in rabbits. Behavioral Neuroscience, 111, 1303-1312.

16. Thompson, L.T. & Disterhoft, J.F. (1997). N-methyl-D-aspartate receptors in associative eyeblink conditioning: Both MK-801 and phencyclidine produce task- and dose-dependent impairments. Journal of Pharmacology and Experimental Therapeutics, 281, 928-940.

17. Carrillo, M.C., Thompson, L.T., Gabrielli, J., & Disterhoft, J.F. (1997). Variation of the intertrial interval in human classical conditioning. Psychobiology, 25, 152-157.

18. Power, J.M., Thompson, L.T., Moyer, J.R., & Disterhoft, J.F. (1997). Enhanced synaptic transmission in CA1 hippocampus after eyeblink conditioning. Journal of Neurophysiology, 78, 1184-1187.

19. Kronforst-Collins, M.A., Moriearty, P.L., Ralph, M., Becker, R.E., Schmidt, B., Thompson, L.T., & Disterhoft, J.F. (1997). Metrifonate treatment enhances acquisition of eyeblink conditioning in aging rabbits. Pharmacology, Biochemistry, and Behavior, 56, 103-110.

20. Thompson, L.T., Moyer, J.R., & Disterhoft, J.F. (1996). Trace eyeblink conditioning demonstrates heterogeneity of learning ability both between and within age groups. Neurobiology of Aging, 17, 619-629.

21. Thompson, L.T., Moyer, J.R., & Disterhoft, J.F. (1996). Transient changes in excitability of rabbit CA3 neurons with a time-course appropriate to support memory consolidation. Journal of Neurophysiology, 76, 1836-1849.

22. Moyer, J.R., Thompson, L.T., & Disterhoft, J.F. (1996). Trace eyeblink conditioning increases CA1 excitability in a transient and learning-specific manner. Journal of Neuroscience, 16, 5536-5546.

23. deJong, G.I., Naber, P.A., van der Zee, E.A., Thompson, L.T., Disterhoft, J.F., & Luiten, P.G.M. (1996). Age-related loss of calcium binding proteins in the rabbit hippocampus. Neurobiology of Aging, 17, 459-465.

24. Disterhoft, J.F., Thompson, L.T., Moyer, J.R., & Mogul, D. (1996). Calcium-dependent afterhyperpolarization and learning in young and aging hippocampus. Life Sciences, 59, 413-420.

25. Disterhoft, J.F., Thompson, L.T., Weiss, C., Moyer, J.R., van der Zee, E., Carrillo, M., Kronforst-Collins, M., & Power, J. (1995). The calcium hypothesis for Alzheimer's disease: Insights from animal and human studies. Neuroscience Research Communications, 17, 121-131.

26. Akase, E., Thompson, L.T., & Disterhoft, J.F. (1994). A system for quantitative analysis of associative learning: 2. Real-time software for MS-DOS microcomputers. Journal of Neuroscience Methods, 54, 119-130.

27. Thompson, L.T., Akase, E., Moyer, J.R. & Disterhoft, J.F. (1994). A system for quantitative analysis of associative learning: 1. Hardware interfaces with cross-species applications. Journal of Neuroscience Methods, 54, 109-117.

28. Disterhoft, J.F., Thompson, L.T., Moyer, J.R., & Kowalska, M. (1993). Nimodipine facilitates learning and increases excitability of hippocampal neurons in aging rabbits. Drugs in Development, 2, 395-405.

29. Disterhoft, J.F., Moyer, J.R., Thompson, L.T., & Kowalska, M. (1993). Functional aspects of calcium-channel modulation. Clinical Neuropharmacology, 16, S12-S24.

30. Thompson, L.T., Moskal, J.R., & Disterhoft, J.F. (1992). Hippocampus-dependent learning facilitated by a monoclonal antibody or D-cycloserine. Nature, 359, 638-641.

31. Moyer, J.R., Thompson, L.T., Black, J.P., & Disterhoft, J.F. (1992). Nimodipine increases excitability of rabbit CA1 pyramidal neurons in an age- and concentration-dependent manner. Journal of Neurophysiology, 68, 2100-2109.

32. Thompson, L.T., Moyer, J.R., & Disterhoft, J.F. (1992). Cellular mechanisms for nimodipine's reduction of aging-related learning deficits. Advances in Behavioral Biology, 40, 241-256.

33. Disterhoft, J.F., Deyo, R.A. & Thompson, L.T. (1992). Nimodipine improves learning and sensorimotor behaviors in aging mammals. Advances in Behavioral Biology, 40, 227-240.

34. Disterhoft, J.F., Black, J., Moyer, J.R. & Thompson, L.T. (1991). Calcium-mediated changes in hippocampal neurons and learning. Brain Research Reviews, 16, 193-220.

35. Thompson, L.T., Deyo, R.A., & Disterhoft, J.F (1990). Nimodipine enhances spontaneous firing of hippocampal pyramidal cells in aging rabbits at a dose that facilitates associative learning. Brain Research, 535, 119-130.

36. Thompson, L.T. & Best, P.J. (1990). Long-term stability of the place field activity of single-units recorded from the dorsal hippocampus of freely-behaving rats. Brain Research, 509, 299-308.

37. Best, P.J. & Thompson, L.T. (1989). Persistence, reticence, and opportunism of place field activity in hippocampal neurons. Psychobiology, 17, 230-235.

38. Disterhoft, J.F., Deyo, R.A., Moyer, J.R., Straube, K.T. & Thompson, L.T. (1989). Calcium blockers and memory in the aging brain. Cardiovascular Reviews & Reports, 10, 22-29.

39. Thompson, L.T. & Best, P.J. (1989). Place cells and silent cells in the hippocampus of freely-behaving rats. Journal of Neuroscience, 9, 2382-2390.

40. Ellins, S.R., Thompson, L.T., & Swanson, W.E. (1983). Effects of novelty and familiarity on illness-induced aversions to food and place cues in coyotes (Canis latrans). Journal of Comparative Psychology, 97, 302-309.

1. Thompson, L.T., Goble, T.J. Farmer, G.E. & Ippolito, C.R. (2006). D-cycloserine enhances location specificity of hippocampal place-cells by enhancing theta-cell and suppressing complex-spike cell firing. Soc. Neurosci. Abstr. 36, 1411.

2. Farmer, G.E., Goble, T.J., Ippolito, C.R. & Thompson, L.T. (2006). Group I metabotropic glutamate receptors alter hippocampal place field activity in freely behaving rats. Soc. Neurosci. Abstr. 36, 4112.

3. Goble, T.J., Farmer, G.E., Ippolito, C.R, Moller, A.R. & Thompson, L.T. (2006). The effects of stress on hippocampal place-fields in a fixed environment: A comparison of physical restraint or dexamethasone to noise exposure. Soc. Neurosci. Abstr. 36, 4113.

4. Seif, T. & Thompson, L.T. (2006). D-cycloserine enhances excitability of hippocampal pyramidal neurons in a novel manner: Evidence for glycine-site saturation. Soc. Neurosci. Abstr. 36, 1019.

5. Bui, H., Shif, Y., Vavrak, P. & Thompson, L.T. (2006). Differential effects of Ca2+ channel blockers and Ca2+ buffering on currents underlying the late AHP in CA1 hippocampal neurons. Soc. Neurosci. Abstr. 36, 820.

6. Gibbons, G.B., Gibbons, J.F. & Thompson, L.T. (2006). Changes in NR2A/NR2B expression and distribution associated with chronic D-cycloserine treatment in vivo. Soc. Neurosci. Abstr. 36, 1020.

7. Lea, P., McColl, R., Maxham, K.Y. & Thompson, L.T. (2006). BOLD changes in cerebellum and hippocampus during pseudo- and trace-eyeblink conditioning in adult humans. Soc. Neurosci. Abstr. 36, 1020.

8. Thompson, L.T., Frank, J., Goble, T.J. & Farmer, G.E. (2005). D-cycloserine enhances location-specificity of hippocampal place-cells. Soc. Neurosci. Abstr. 35.

9. Goble, T.J., Frank, J.R., Farmer, G.E., Moller, A.R. & Thompson, L.T. (2005). Stress- and noise-induced plasticity of hippocampal place-fields in a fixed environment. Soc. Neurosci. Abstr. 35.

10. Williford, C. & Thompson, L.T. (2005). Insulin enhances excitability of CA1 pyramidal neurons in vitro. Soc. Neurosci. Abstr. 35.

11. Seif, T. & Thompson, L.T. (2005). D-cycloserine increases hippocampal excitability. Soc. Neurosci. Abstr. 35.

12. Bui, H., Patel, A. & Thompson, L.T. (2005). Effects of dequalinium on currents underlying the late AHP in CA1 hippocampal neurons. Soc. Neurosci. Abstr. 35.

13. Lea, P., McColl, R., Maxham, K.Y. & Thompson, L.T. (2005). BOLD signal changes in the hippocampus and cerebellum during trace eyeblink conditioning. Soc. Neurosci. Abstr. 35.

14. Seif, T. & Thompson, L.T. (2004). D-cycloserine enhances CA1 neuronal excitability in vitro. Soc. Neurosci. Abstr. 30, 301.

15. Goble, T.J., Farmer, G.E., Frank, J., Moller, A.R. & Thompson, L.T. (2004). Acute noise exposure alters hippocampal place-fields: Evidence for extralemniscal sensory pathway plasticity. Soc. Neurosci. Abstr. 30, 303.

16. Thompson, L.T. & Gant, J.C. (2003). Learning-specific reduction of CA1 neuron AHPs in rat spatial learning: Aging-specific effects. Soc. Neurosci. Abstr. 29, 719.

17. Bui, W. & Thompson, L.T. (2003). Altering neuronal excitability in vitro, testing in vivo: A protocol to test treatments improving learning and memory. Soc. Neurosci. Abstr. 29, 720.

18. Lea, P., McColl, R., Maxham, K.Y. & Thompson, L.T. (2003). Linking eyeblink conditioning deficits to age-specific changes in regional blood flow using fMRI. Soc. Neurosci. Abstr. 29, 731.

19. Greer, T., Trivedi, M. & Thompson, L.T. (2003). Automatic processing deficits found in absence of effortful processing deficits in clinical depression. Clin. Neuropsych. Soc. Abst. 55, 400.

20. Gant, C., & Thompson, L.T. (2002). Calmodulin-mediated neuronal excitability, calmodulin protein expression, and learning in the aging hippocampus. Soc. Neurosci. Abstr., 28, 333.

21. Bui, W. & Thompson, L.T. (2002). Age- and strain-dependent heterogeneity in acquisition of a forced-choice long-delay win-stay spatial-learning maze task. Soc. Neurosci. Abstr., 28, 333.

22. Lea, P., McColl, R., Maxham, K.Y. & Thompson, L.T. (2002). Optimizing signal detection in event related fMRI during eyeblink onditioning: Differential age-, stimulus-, and associative-learning dependent changes in BOLD signals. Soc. Neurosci. Abstr., 28, 414.

23. Greer, T. & Thompson, L.T. (2002). Clinical depression impairs performance on both delay and trace eyeblink conditioning. Soc. Neurosci. Abstr., 28, 845.

24. Gant, C., & Thompson, L.T. (2001). Calmodulin influences neural excitability through interaction with SK channels in hippocampal CA1 neurons. Soc. Neurosci. Abstr., 27, 1023.

25. Lea, P., McColl, R., Maxham, K.Y. & Thompson, L.T. (2001). Event related fMRI during eyeblink conditioning: Differential age-, stimulus-, and associative-learning dependent changes in BOLD signals. Soc. Neurosci. Abstr., 27, 94.

26. Greer, T. & Thompson, L.T. (2001). The use of eyeblink conditioning to elicit latent inhibition in depressed and nondepressed individuals. Soc. Neurosci. Abstr., 27, 95.

27. Thompson, L.T., Gant, C., & Lea, P. (2000). Postsynaptic plasticity in young and aging rat CA1 neurons and spatial learning: Further emphasis on accommodation. Soc. Neurosci. Abstr., 26, 18.

28. Gant, C. & Thompson, L.T. (2000). Calmodulin mediated plasticity in rat CA1 neurons following spatial learning. Soc. Neurosci. Abstr., 26, 18.

29. Lea, P., McColl, R., Maxham, K.Y. & Thompson, L.T. (2000). Aging and event related fMRI during eyeblink onditioning. Soc. Neurosci. Abstr., 26, 984.

30. Greer, T. & Thompson, L.T. (2000). Multiple eyeblink conditioning tasks in both aging & cognitively impaired individuals. Soc. Neurosci. Abstr., 26, 984.

31. Greer, T.L. & Thompson, L.T. (1999). Depression and memory: Eyeblink conditioning and studies with depressed individuals. Soc. Neurosci. Abstr., 25, 839.

32. Gant, C., Glasier, C., Lea, P., Wood, J.G. & Thompson, L.T. (1999). Age-dependent changes in Ca2+-mediated excitability in rat CA1 neurons correlate with changes in radial arm maze learning. Soc. Neurosci. Abstr. 25, 356.

33. Vachha, B., Velasco, R., Boonpattrawong, M. & Thompson, L.T. (1999). Aging alters CaM-KII and calcineurin immunoreactivity in rat hippocampus. Soc. Neurosci. Abstr. 25, 356

34. Greer, T.L. & Thompson, L.T. (1998). Converging models: Correlating human eyeblink conditioning performance with neuropsychological measures. Soc. Neurosci. Abstr. 24, 163.

35. Thompson, L.T. (1998). D-cycloserine and spatial maze learning by young and aging rats. Soc. Neurosci. Abstr. 24, 2122.

36. Oh, M.M., Power, J.M., Thompson, L.T., Moriearty, P.L., & Disterhoft, J.F. (1998). Metrifonate increases CA1 neuronal excitability. Soc. Neurosci. Abstr. 24, 1335.

37. Thompson, L.T. & Disterhoft, J.F. (1997). Age- and dose-dependent facilitation of associative eyeblink conditioning by D-cycloserine. Soc. Neurosci. Abstr. 23, 218.

38. Oh, M.M., Power, J.M., Thompson, L.T., & Disterhoft, J.F. (1997). Apamin decreases the afterhyperpolarization in rabbit CA1 neurons. Soc. Neurosci. Abstr. 23, 1745.

39. Kronforst, M.A., Moriearty, P.L., Ralphs, M., Becker, R.E., Schmidt, B., Thompson, L.T., & Disterhoft, J.F. (1995). Facilitation of learning in the aging rabbit after chronic metrifonate treatment. Soc. Neurosci. Abstr. 21, 196.

40. Power, J.M., Thompson, L.T., Moyer, J.R., & Disterhoft, J.F. (1995). Increased synaptic responsiveness between CA3 and CA1 after trace eyeblink conditioning recorded in vitro. Soc. Neurosci. Abstr. 21, 1931.

41. Thompson, L.T., Moyer, J.R., & Disterhoft, J.F. (1995). Rabbits demonstrate age-dependent heterogeneity of learning ability in trace eyeblink conditioning. Soc. Neurosci. Abstr. 21, 196.

42. Carillo, M., Thompson, L.T., Gabrielli, J.D.E., Naughton, B.J., Heller, A. & Disterhoft, J.F. (1994). Nimodipine enhances trace eyeblink conditioning in aging humans. Soc. Neurosci. Abstr. , 20, 387.

43. Disterhoft, J.F., Moyer, J.R., Thompson, L.T., Cutting, F.B., & Power, J.M. (1994). In vitro analyses of aging-related learning deficits. Soc. Neurosci. Abstr. 20, 796.

44. Moyer, J.R., Thompson, L.T., & Disterhoft, J.F. (1994). The hippocampus as an intermediate storage buffer after associative learning: In vitro evidence from rabbit CA1. Soc. Neurosci. Abstr. 20, 796.

45. Power, J.M., Moyer, J.R., Thompson, L.T., dal Canto, M.C. & Disterhoft, J.F. (1994). Trace eyeblink conditioning increases synaptic efficacy between CA3 and CA1 in vitro. Soc. Neurosci. Abstr. 20, 796.

46. Thompson, L.T. & Disterhoft, J.F. (1994). Partial agonists of the glycine site on the NMDA receptor facilitate eyeblink conditioning in aging rabbits. Annual Winter Conference on Neurobiology of Learning & Memory, Park City, UT.

47. Thompson, L.T., Moyer, J.R. & Disterhoft, J.F. (1994). Learning (not performance or memory) increases in vitro excitability of hippocampal CA3 neurons. Soc. Neurosci. Abstr. 20, 796.

48. Carrillo, M.C., Thompson, L.T., Naughton, B., Gabrieli, J. & Disterhoft, J.F. (1993). Aging impairs trace eyeblink conditioning in humans independent of changes in the unconditioned response. Soc. Neurosci. Abstr. 19, 386.

49. Disterhoft, J.F., Moyer, J.R., Thompson, L.T. & Kowalska, M. (1993). Calcium and brain aging: Behavioural aspects. Second Camillo Golgi Conference on Neuroscience, Ponte di Legno, Italy.

50. Disterhoft, J.F., Moyer, J.R., Thompson, L.T. & Kowalska, M. (1993). Calcium and learning in aging brain. Fifth Winter Conference on Neural Plasticity, St. Lucia.

51. Disterhoft, J.F., Thompson, L.T. & Moyer, J.R. (1993). The role of neuronal calcium in aging-related learning impairments. The calcium hypothesis of aging and dementia, National Inst. of Aging Symposium, NIH, Bethesda, MD.

52. Disterhoft, J.F., Thompson, L.T., Halperin, G.I. & Lanthorn, T. (1993). D-cycloserine enhances hippocampally-dependent eyeblink conditioning in aging as well as young rabbits. Soc. Neurosci. Abstr. 19, 1009.

53. Moyer, J.R., Thompson, L.T. & Disterhoft, J.F. (1993). Hippocampally-dependent trace eyeblink conditioning increases excitability of rabbit CA1 neurons in vitro. Soc. Neurosci. Abstr. 19, 801.

54. Naber, P.A., Thompson, L.T., Luiten, P.G.M. & Disterhoft, J.F. (1993). Age-related expression of calbindin D-28K and parvalbumin immunoreactivity in the rabbit hippocampus. Soc. Neurosci. Abstr. 19, 388.

55. Thompson, L.T., Moyer, J.R., Trommer, B. & Disterhoft, J.F. (1993). Hippocampally-dependent eyeblink conditioning also increases excitability of rabbit CA3 neurons in vitro.