My publications in the scientific literature
(published under my full name, Lucien T. Thompson):

[Click on the underlined links below to download the full-text .pdf version of these papers]

Peer-reviewed papers

  1. Greer, T.L., Trivedi, M.H. & Thompson, L.T. (2005). Impaired delay and trace eyeblink conditioning performance in major depressive disorder. Journal of Affective Disorders, 86, 235-245.
  2. Moller, A.R. & Thompson, L.T. (2003). Central neuronal plasticity in tinnitus: Functional assessments in the inferior colliculus and the hippocampus. Tinnitus Today, 28, 20.
  3. Thompson, L.T., Lea, P. & Bui, W. Strain-dependent differences in age-dependent spatial learning: Defining 'impaired'. Neurobiology of Aging, in preparation.
  4. Thompson, L.T. & Gant, J.C. Spatial learning and regulation of post-synaptic excitability: A preserved mechanism expressed in young and aging CA1 neurons. Journal of Neuroscience, in preparation.
  5. Gant, J.C. & Thompson, L.T. Calmodulin inhibitors enhance post-synaptic excitability in young and aging CA1 neurons. Journal of Neurophysiology, in preparation.
  6. Thompson, L.T. & Lea, P. D-cycloserine facilitates complex spatial learning in rats: Age- and dose-dependence of effects. Behavioral Neuroscience, in preparation.
  7. Greer, T.L. & Thompson, L.T. Associative eyeblink conditioning and aging: Cross-sectional analyses of deficits in discrimination and reveral learning. Behavioral Neuroscience, in revision.
  8. Thompson, L.T., Gant, J.C., Velasco, R., & Vachha, B. Aging reverses complementary expression of CaM-KII and calcineurin immunoreactivity in rat hippocampus. Hippocampus, in preparation.
  9. Disterhoft, J.F., Carrillo, M.C., Thompson, L.T., McNaughton, B., & Gabrielli, J. Nimodipine reverses impairments in eyeblink conditioning in the most impaired but clinically 'normal' aging humans. Psychobiology, in preparation.
  10. Oh, M.M., Power, J.M., Thompson, L.T., & Disterhoft, J.F. (2000). Apamin increases the excitability of rabbit CA1 hippocampal pyramidal neurons. Neuroscience Research Communications, 27, 135-142.
  11. Moyer, J.R., Jr., Power, J.M., Thompson, L.T. & Disterhoft, J.F. (2000). Increased excitability of aged rabbit CA1 neurons after trace eyeblink conditioning. Journal of Neuroscience, 20, 5476-5482.
  12. Oh, M.M., Power, J.M., Thompson, L.T., & Disterhoft, J.F. (1999). Metrifonate reduces post-burst afterhyperpolarizations in aging CA1 neurons. Journal of Neuroscience, 19, 1814-1823.
  13. Thompson, L.T. & Disterhoft, J.F. (1997). Age- and dose-dependent facilitation of associative eyeblink conditioning by D-cycloserine in rabbits. Behavioral Neuroscience, 111, 1303-1312.
  14. Thompson, L.T. & Disterhoft, J.F. (1997). N-methyl-D-aspartate receptors in associative eyeblink conditioning: Both MK-801 and phencyclidine produce task- and dose-dependent impairments. Journal of Pharmacology and Experimental Therapeutics, 281, 928-940.
  15. Carrillo, M.C., Thompson, L.T., Gabrielli, J., & Disterhoft, J.F. (1997). Variation of the intertrial interval in human classical conditioning. Psychobiology, 25, 152-157.
  16. Power, J.M., Thompson, L.T., Moyer, J.R., Jr., & Disterhoft, J.F. (1997). Enhanced synaptic transmission in CA1 hippocampus after eyeblink conditioning. Journal of Neurophysiology, 78, 1184-1187.
  17. Kronforst-Collins, M.A., Moriearty, P.L., Ralph, M., Becker, R.E., Schmidt, B., Thompson, L.T., & Disterhoft, J.F. (1997). Metrifonate treatment enhances acquisition of eyeblink conditioning in aging rabbits. Pharmacology, Biochemistry, and Behavior, 56, 103-110.
  18. Thompson, L.T., Moyer, J.R., Jr., & Disterhoft, J.F. (1996). Trace eyeblink conditioning demonstrates heterogeneity of learning ability both between and within age groups. Neurobiology of Aging, 17, 619-629.
  19. Thompson, L.T., Moyer, J.R., Jr., & Disterhoft, J.F. (1996). Transient changes in excitability of rabbit CA3 neurons with a time-course appropriate to support memory consolidation. Journal of Neurophysiology, 76, 1836-1849.
  20. Moyer, J.R., Jr., Thompson, L.T., & Disterhoft, J.F. (1996). Trace eyeblink conditioning increases CA1 excitability in a transient and learning-specific manner. Journal of Neuroscience, 16, 5536-5546.
  21. deJong, G.I., Naber, P.A., van der Zee, E.A., Thompson, L.T., Disterhoft, J.F., & Luiten, P.G.M. (1996). Age-related loss of calcium binding proteins in the rabbit hippocampus. Neurobiology of Aging, 17, 459-465.
  22. Disterhoft, J.F., Thompson, L.T., Moyer, J.R., Jr., & Mogul, D. (1996). Calcium-dependent afterhyperpolarization and learning in young and aging hippocampus. Life Sciences, 59, 413-420.
  23. Disterhoft, J.F., Thompson, L.T., Weiss, C., Moyer, J.R., Jr., van der Zee, E., Carrillo, M., Kronforst-Collins, M., & Power, J. (1995). The calcium hypothesis for Alzheimer's disease: Insights from animal and human studies. Neuroscience Research Communications, 17, 121-131.
  24. Akase, E., Thompson, L.T., & Disterhoft, J.F. (1994). A system for quantitative analysis of associative learning: 2. Real-time software for MS-DOS microcomputers. Journal of Neuroscience Methods, 54, 119-130.
  25. Thompson, L.T., Akase, E., Moyer, J.R., Jr. & Disterhoft, J.F. (1994). A system for quantitative analysis of associative learning: 1. Hardware interfaces with cross-species applications. Journal of Neuroscience Methods, 54, 109-117.
  26. Disterhoft, J.F., Thompson, L.T., Moyer, J.R., Jr., & Kowalska, M. (1993). Nimodipine facilitates learning and increases excitability of hippocampal neurons in aging rabbits. Drugs in Development, 2, 395-405.
  27. Disterhoft, J.F., Moyer, J.R., Jr., Thompson, L.T., & Kowalska, M. (1993). Functional aspects of calcium-channel modulation. Clinical Neuropharmacology, 16, S12-S24.
  28. Thompson, L.T., Moskal, J.R., & Disterhoft, J.F. (1992). Hippocampus-dependent learning facilitated by a monoclonal antibody or D-cycloserine. Nature, 359, 638-641.
  29. Moyer, J.R., Jr., Thompson, L.T., Black, J.P., & Disterhoft, J.F. (1992). Nimodipine increases excitability of rabbit CA1 pyramidal neurons in an age- and concentration-dependent manner. Journal of Neurophysiology, 68, 2100-2109.
  30. Thompson, L.T., Moyer, J.R., Jr., & Disterhoft, J.F. (1992). Cellular mechanisms for nimodipine's reduction of aging-related learning deficits. Advances in Behavioral Biology, 40, 241-256.
  31. Disterhoft, J.F., Deyo, R.A. & Thompson, L.T. (1992). Nimodipine improves learning and sensorimotor behaviors in aging mammals. Advances in Behavioral Biology, 40, 227-240.
  32. Disterhoft, J.F., Black, J., Moyer, J.R., Jr. & Thompson, L.T. (1991). Calcium-mediated changes in hippocampal neurons and learning. Brain Research Reviews, 16, 193-220.
  33. Thompson, L.T., Deyo, R.A., & Disterhoft, J.F (1990). Nimodipine enhances spontaneous firing of hippocampal pyramidal cells in aging rabbits at a dose that facilitates associative learning. Brain Research, 535, 119-130.
  34. Thompson, L.T. & Best, P.J. (1990). Long-term stability of the place field activity of single-units recorded from the dorsal hippocampus of freely-behaving rats. Brain Research, 509, 299-308.
  35. Best, P.J. & Thompson, L.T. (1989). Persistence, reticence, and opportunism of place field activity in hippocampal neurons. Psychobiology, 17, 230-235.
  36. Disterhoft, J.F., Deyo, R.A., Moyer, J.R., Jr., Straube, K.T. & Thompson, L.T. (1989). Calcium blockers and memory in the aging brain. Cardiovascular Reviews & Reports, 10, 22-29.
  37. Thompson, L.T. & Best, P.J. (1989). Place cells and silent cells in the hippocampus of freely-behaving rats. Journal of Neuroscience, 9, 2382-2390.
  38. Ellins, S.R., Thompson, L.T., & Swanson, W.E. (1983). Effects of novelty and familiarity on illness-induced aversions to food and place cues in coyotes (Canis latrans). Journal of Comparative Psychology, 97, 302-309.

Reviews

  1. Disterhoft, J.F., Kronforst, M.A., Moyer, J.R., Jr., Thompson, L.T., van der Zee, E., & Weiss, C. (1996). Hippocampal neurons changes during trace eyeblink conditioning in the rabbit. In J.R. Bloedel, T.J. Ebner, & S.P. Wide (Eds.), The acquisition of motor behavior in vertebrates. Cambridge, MA: MIT Press, pp. 143-174.
  2. Disterhoft, J.F., Moyer, J.R., Jr., & Thompson, L.T. (1994). The calcium rationale in aging and Alzheimer's disease: Evidence from an animal model of normal aging. Annals of the New York Academy of Sciences, 747, 382-406.
  3. Disterhoft, J.F., Thompson, L.T., & Moyer, J.R., Jr. (1994). Cellular mechanisms of associative learning in the hippocampus. In J. Delacour (Ed.), The memory system in the brain. London: World Scientific Publishing, pp. 431-492.
  4. Disterhoft, J.F., Moyer, J.R., Jr., Thompson, L.T., & Kowalska, M. (1993). Nimodipine and learning in aging rabbits. In J. Traber (Ed.), Dihydropyridines: Progress in pharmacology and therapy. Berlin: Springer-Verlag, pp. 81-97.
  5. Disterhoft, J.F., Black, J., Deyo, R.A., Straube, K., & Thompson, L.T. (1989). Associative learning in aging rabbits is facilitated by nimodipine. In W.H. Gispen & J. Traber (Ed.), Nimodipine and central nervous function. Stuttgart: Schattauer.

Selected abstracts (out of 90):

  1. Thompson, L.T. Frank, J., Goble, T.J. & Farmer, G.E. (2005). D-cycloserine enhances location-specificity of hippocampal place-cells. Soc. Neurosci. Abstr. 35.
  2. Goble, T.J., Frank, J.R., Farmer, G.E., Moller, A.R. & Thompson, L.T. (2005). Stress- and noise-induced plasticity of hippocampal place-fields in a fixed environment. Soc. Neurosci. Abstr. 35.
  3. Williford, C. & Thompson, L.T. (2005). Insulin enhances excitability of CA1 pyramidal neurons in vitro. Soc. Neurosci. Abstr. 35.
  4. Seif, T. & Thompson, L.T. (2005). D-cycloserine increases hippocampal excitability. Soc. Neurosci. Abstr. 35.
  5. Bui, H., Patel, A. & Thompson, L.T. (2005). Effects of dequalinium on currents underlying the late AHP in CA1 hippocampal neurons. Soc. Neurosci. Abstr. 35.
  6. Lea, P., McColl, R., Maxham, K.Y. & Thompson, L.T. (2005). BOLD signal changes in the hippocampus and cerebellum during trace eyeblink conditioning. Soc. Neurosci. Abstr. 35.
  7. Goble, T.J., Farmer, G.E., Frank, J., Moller, A.R. & Thompson, L.T. (2004). Acute noise exposure alters hippocampal place-fields: Evidence for extralemniscal pathway plasticity. Soc. Neurosci. Abstr. 34.
  8. Seif, T. & Thompson, L.T. (2004). D-Cycloserine (DCS) enhances CA1 neuronal excitability in vitro. Soc. Neurosci. Abstr. 34.
  9. Greer, T., Trevedi, M. & Thompson, L.T. (2003). Automatic processing deficits found in absence of effortful processing deficits in clinical depression. Clinical Neuropsych. Soc. Abstr. 55.
  10. Gant, C., & Thompson, L.T. (2002). Calmodulin-mediated neuronal excitability, calmodulin protein expression, and learning in the aging hippocampus. Soc. Neurosci. Abstr., 32.
  11. Bui, W. & Thompson, L.T. (2002). Age- and strain-dependent heterogeneity in acquisition of a forced-choice long-delay win-stay spatial-learning maze task. Soc. Neurosci. Abstr., 32.
  12. Bendkhale, M. & Thompson, L.T. (2002). Onset of age-dependent alterations in hippocampal place field activity. Soc. Neurosci. Abstr., 32.
  13. Lea, P., McColl, R., Maxham, K.Y. & Thompson, L.T. (2002). Optimizing signal detection in event related fMRI during eyeblink onditioning: Differential age-, stimulus-, and associative-learning dependent changes in BOLD signals. Soc. Neurosci. Abstr., 32.
  14. Greer, T. & Thompson, L.T. (2002). Clinical depression impairs performance on both delay and trace eyeblink conditioning. Soc. Neurosci. Abstr., 32.
  15. Gant, C., & Thompson, L.T. (2001). Calmodulin influences neural excitability through interaction with SK channels in hippocampal CA1 neurons. Soc. Neurosci. Abstr., 31.
  16. Lea, P., McColl, R., Maxham, K.Y. & Thompson, L.T. (2001). Event related fMRI during eyeblink onditioning: Differential age-, stimulus-, and associative-learning dependent changes in BOLD signals. Soc. Neurosci. Abstr., 31.
  17. Greer, T. & Thompson, L.T. (2001). The use of eyeblink conditioning to elicit latent inhibition in depressed and nondepressed individuals. Soc. Neurosci. Abstr., 31.
  18. Thompson, L.T., Gant, C., & Lea, P. (2000) Postsynaptic plasticity in young and aging rat CA1 neurons and spatial learning: Further emphasis on accommodation. Soc. Neurosci. Abstr., 30.
  19. Gant, C. & Thompson, L.T. (2000) Calmodulin mediated plasticity in rat CA1 neurons following spatial learning. Soc. Neurosci. Abstr., 30.
  20. Velasco, R., Gant, C. & Thompson, L.T. (2000) Age-dependent changes in mRNA expression of a calcium calmodulin-dependent kinase and phosphatase in rat hippocampus. Soc. Neurosci. Abstr., 30.
  21. Lea, P. McColl, R., Maxham, K.Y. & Thompson, L.T. (2000). Aging and event related fMRI during eyeblink conditioning. Soc. Neurosci. Abstr., 30.
  22. Greer, T. & Thompson, L.T. (2000). Multiple eyeblink conditioning tasks in both aging and cognitively impaired individuals. Soc. Neurosci. Abstr., 30.
  23. Thompson, L.T. (2000). Age associated alterations in hippocampal neurons and learning: Role of calmodulin. Spring Hippocampal Research Conference, Grand Caymans.
  24. Lea, P., McColl, R., Maxham, K. & Thompson, L.T. (2000). Aging and event related fMRI during classical eyeblink conditioning. International Behav. Neurosci. Soc. Abstr.
  25. Gant, JC., Lea, P. & Thompson, L.T. (2000). Age-dependent Ca2+-mediated excitability in rat CA1 neurons predicts radial arm maze learning. International Behav. Neurosci. Soc. Abstr.
  26. Greer, T.L. & Thompson, L.T. (1999). Depression and memory: Eyeblink conditioning and cognitive studies with depressed individuals. Soc. Neurosci. Abstr., 29, 839.
  27. Gant, C., Glasier, C., Lea, P., Wood, J.G. & Thompson, L.T. (1999). Age-dependent changes in Ca2+-mediated excitability in rat CA1 neurons correlate with changes in radial arm maze learning. Soc. Neurosci. Abstr., 29, 356.
  28. Vachha, B., Velasco, R., Boonpattrawong, M. & Thompson, L.T. (1999). Aging alters CaM-KII and calcineurin immunoreactivity in rat hippocampus. Soc. Neurosci. Abstr., 29, 356.
  29. Greer, T.L. & Thompson, L.T. (1998). Converging models: Correlating human eyeblink conditioning performance with neuropsychological measures. Soc. Neurosci. Abstr., 28, 1287.
  30. Thompson, L.T. (1998). D-cycloserine and spatial maze learning by young and aging rats. Soc. Neurosci. Abstr., 28, 902.
  31. Carillo, M.C., Thompson, L.T., Gabrielli, J.D.E., Naughton, B.J., Heller, A., & Disterhoft, J.F. (1994). Nimodipine enhances trace eyeblink conditioning in aging humans. Soc. Nesc. Abstr., 24, 387.
  32. Carrillo, M.C., Thompson, L.T., Naughton, B., Gabrieli, J., & Disterhoft, J.F. (1993). Aging impairs trace eyeblink conditioning in humans independent of changes in the unconditioned response. Soc. Neurosci. Abstr., 23, 386.
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Last updated July 20, 2005, 6:50 a.m.