Intracellular hormone receptors

19_18
Pathways of corticosteroid biosynthesis. The steroidogenic pathways used in the biosynthesis of the corticosteroids are shown, along with the structures of the intermediates and products. The pathways that are unique to the zona glomerulosa are shown in blue, whereas those unique to the zonae fasciculata/reticularis are shown in gray. P450scc, cholesterol side-chain cleavage; 3-beta-HSD, 3-beta-hydroxysteroid dehydrogenase; P45017-alpha, steroid 17-alpha-hydroxylase; P45021, steroid 21-hydroxylase; P450aldo, aldpsterone synthase; P45011-beta, steroid 11-beta-hydroxylase.