The University of Texas at Dallas School of Behavioral and Brain Sciences

Xiaosi Gu

Assistant Professor

Research Interests

The neural and computational mechanisms underlying human beliefs, decision making, and social interaction in both health and disease.

Curriculum Vitae


Email: [email protected]
Phone: 214-905-3007
Office: CBH_2.248
Campus Mail Code: CBH 10
Website: Computational Psychiatry Unit


Dr. Xiaosi Gu is one of the foremost researchers in the area of computational psychiatry. Her research examines the neural and computational mechanisms underlying human beliefs, decision making, and social interaction, in both health and disease, through a synthesis of neuroimaging and computational modeling. Recently, Dr. Gu has been examining the interaction between beliefs and drugs in drug addiction. This work suggests that beliefs about drugs could override the effects of drugs on neural responses to reward. Dr. Gu began her neuroimaging research at the Department of Psychology at Peking University (PKU), Beijing. After receiving a dual degree in psychology and economics from PKU, she moved to New York City to pursue a PhD in Neuroscience at the Mount Sinai School of Medicine. Dr. Gu then completed her postdoctoral training in computational psychiatry and decision neuroscience at the Virginia Tech Carilion Research Institute, Roanoke, VA and the Wellcome Trust Centre for Neuroimaging at University College London (UCL), London, UK. During her time in London, she also set up the world’s first computational psychiatry course at UCL.

Recent and Selected Representative Publications

Recent Articles in Peer-Refereed Journals

Gu, X., Lohrenz, T., Salas, R., Baldwin, P.R., Soltani, A., Kirk, U., Cinciripini, P.M., Montague, P.R. (2015) Belief about nicotine selectively modulates value and reward prediction error signals in smokers. Proceedings of the National Academy of Sciences U.S.A. 2015 Feb 24;112(8):2539-44. doi: 10.1073/pnas.1416639112.

Gu, X., Wang, X., Hula, A., Wang, S., Xu, S., Lohrenz, T.M., Knight, R.T., Gao, Z., Dayan, P., Montague, P.R. (2015). Necessary, yet dissociable contributions of the insular and ventromedial prefrontal cortices to norm adaptation: computational and lesion evidence in humans. The Journal of Neuroscience. 2015 Jan 14;35(2):467-73. doi: 10.1523/JNEUROSCI.2906-14.2015.

Gu X., FitzGerald, T.H. (2014) Interoceptive inference: homeostasis and decision-making. Trends in Cognitive Sciences. doi: 10.1016/j.tics.2014.02.001.