The University of Texas at Dallas School of Behavioral and Brain Sciences

Francesca M. Filbey

Professor
Bert Moore Chair in BrainHealth

Research Interests

Neurobiological mechanisms underlying reward-motivation

Curriculum Vitae

Contact

Email: [email protected]
Phone: 972-883-3311
Office: CBH_2.720
Campus Mail Code: CBH 10
Website: Filbey Lab

Biography

Dr. Francesca Filbey is a leading researcher in the area of cognitive neuroscience of addiction, applying human neuroimaging tools (MRI, EEG) to examine processes related to mesocorticolimbic network function, such as reward and motivation, cognitive effort and self-monitoring. Using addiction as a model of brain plasticity, she investigates the neurobiological antecedents and consequences of substance use in these processes. Her research led to the first neurobiological characterization of cannabis cue-reactivity (Filbey et al., 2009; Filbey et al., 2010) and the role of endocannabinoid genes in response to cannabis. Her current research characterizes the mechanisms that underlie reward sensitivity to cannabis and identifies individual and environmental modulators of these mechanisms. Other areas of interest include clinical studies determining the mediating role of mesocorticolimbic network function in several disorders following exposure to cannabinoid receptor 1 (CB1) modulators, and, identification of markers of risk and treatment response in opioid use disorder. Dr. Filbey is the author of Neuroscience of Addiction (In Press, Cambridge University Press). Dr. Filbey received her PhD at King’s College London, United Kingdom and completed her post-doctoral training at the NIH.

Recent and Selected Representative Publications

Recent Articles in Peer-Refereed Journals

Filbey, F. M., Aslan, S., Lu, H., & Peng, S. L. (2018). Residual Effects of THC via Novel Measures of Brain Perfusion and Metabolism in a Large Group of Chronic Cannabis Users. Neuropsychopharmacology, 43(4), 700-707. doi:10.1038/npp.2017.44.

Prashad, S., Dedrick, E. S., To, W. T., Vanneste, S., & Filbey, F. M. (2018). Testing the role of the posterior cingulate cortex in processing salient stimuli in cannabis users: an rTMS study. Eur J Neurosci. doi:10.1111/ejn.14194.

Filbey, F. M., Dunlop, J., Ketcherside, A., Baine, J., Rhinehardt, T., Kuhn, B., . . . Alvi, T. (2016). fMRI study of neural sensitization to hedonic stimuli in long-term, daily cannabis users. Hum Brain Mapp, 37(10), 3431-3443. doi:10.1002/hbm.23250.

Filbey, F.M., Aslan, S., Calhoun, V., Spence, J.S., Dasmaraju, E., Caprihan, A., and Segall, J. (2014). Long-term effects of marijuana use on the brain. Proceedings of the National Academy of Sciences, 111 (47): 16913-16918. doi: 10.1073/pnas.1415297111.

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