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Control of Appetite and Mood: Biology's Royston C. Clowes Lecture
Thursday, Mar 27, 2014
4 p.m. - 5:30 p.m. Location: FN 2.102

The Department of Molecular and Cell Biology presents

25th  Royston C. Clowes Lecture Series

Jeffery M. Zigman, M.D., Ph.D., The Diana and Richard C. Strauss Professorship in Biomedical Research; Mr. and Mrs. Bruce G. Brookshire Professorship in Medicine, Associate Professor, Internal Medicine, Psychiatry, UT Southwestern Medical Center.

Presentation:  Control of Appetite and Mood in Mouse and Man by the Hormone Ghrelin

In this lecture, I will discuss different forms of appetite and eating behavior in people and their possible relationships to mood and stress.  I will also highlight our own work using mouse models to study the mechanisms controlling these phenomena, and in particular their control by the gastric hormone ghrelin.  By the end of the lecture, I hope that the attendees will have learned 4 key points:

  1. Ghrelin signaling pathways contribute to several different types of eating, including eating for survival, eating for pleasure and eating in response to stress.
  2. Ghrelin may serve as a molecular signal linking stress, mood and metabolism
  3. A distributed network of central nervous system sites exist that directly mediate the effects of ghrelin on eating behaviors. 
  4. Investigating the mechanism of ghrelin action has revealed a potential new class of drugs to treat depression.


Contact Info:
Victoria Winters, 972-883-2514
Questions? Email me.

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